Translational Medicine and Bioengineering

Translational Hematology

People may be affected by many different types of blood conditions and blood cancers. Common blood disorders include anaemia, Clotting and bleeding disorders such as hemophilia blood clots, and blood cancers such as leukemia, lymphoma, and myeloma. Clinical research emphasize the paradox that both anemia and transfusion are associated with organ injury and increased morbidity and mortality across a wide span of disease states and surgical interventions. Among the other blood disorders. Leukemia is the most common form of cancer in children, affecting about 3,000 children each year in the United States, accounting for about 30 percent of childhood cancers.

Functional and translational genomic sequencing will be used to investigate mechanisms of globin gene regulation and proteomics to study the red blood cell membrane function in health and disease. A blood and marrow transplant replaces a person's abnormal stem cells with healthy ones from another person (a donor). This procedure allows the recipient to get new stem cells that work properly.