Translational Modeling of Efficacy and Safety

Animal and Translational Models for CNS Drug Discovery combines the experience of academic, clinical and pharmaceutical neuroscientists in a unique collaborative approach to provide a greater understanding of the relevance of animal models of neuropsychiatric disorders and their role as translational tools for the discovery of CNS drugs being developed for the treatment of these disorders. Translation models describe the mathematical relationship between two or more languages. We call them models of translational equivalence because the main thing that they aim to predict is whether expressions in different languages have equivalent meanings.

The goal of translational research is to advance basic research and new technology toward clinical utility. Molecular diagnostics focuses primarily on nucleic acids. Rapid advances in molecular diagnostics both enable basic research and result in clinical diagnostic tests. The aim of translational research is to take the outcomes and innovations developed within the research context into clinical practice. A prototype is an early sample, model, or release of a product built to test a concept or process or to act as a thing to be replicated or learned from. Prototyping is the design verification phase of Product Development -- used to demonstrate or prove aspects of a design. Prototyping is simply taking the design from the virtual, imaginary realm into the physical world.

  • Initial identification of the intervention idea
  • Product prototype development
  • Testing for safety, accuracy and efficacy in model systems
  • Several types of clinical trials
  • Diagnostic tests and translational research

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