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Alexander Melerzanov

Alexander Melerzanov

Moscow Physico-Technical University, Russia

Title: Translational medicine for interventional cardiology and angiology. Organizational issues

Biography

Biography: Alexander Melerzanov

Abstract

Usual perception of the translational medicine is based on OMICs technologies approach to the personalized medicine. In our center we make an attempt to expand the understanding of translational medicine towards mathematical modelling of circulatory system as another base for personalized treatment. Modern visualization means combined with effective algorithms of automated processing of diagnostics data allow construction of individual computational grids for surgery planning and treatment optimization. Development and implementation into clinical practice of devices with s.c. ”hardware-software systems” minimizes diagnostic invasion by using of math modelling of the blood stream and cardiac workload. This way we plan to achieve as better treatment outcome including surgery itself and follow up protocols and as a next step we see development of the individualized implanted devices based on stretchable electronics. For that work we have established a translational medicine department. Department consists of physicians and scientists joint by two leading Russian technical and medical universities (Moscow Institute of Physics and Technology (State Research University) and First Moscow State Medical University named after I.M.Sechenov respectively) and George Washington University. The plan of Ministry of Healthcare of Russian Federation is to establish a chain of translational medicine centers. We are the first one due to the fact the cardio-circulatory diseases are by far (58%) overcome all other reasons for mortality in Russia. Implementation of translational medicine into practical healthcare became possible after the new law acceptance. New law allows medical professionals to apply novel scientific approaches to practice based on the decision of the ethic committee with funding from the Ministry of Healthcare. New approach will change the existing approach to interventional angiology, will have a pronounced as medical care quality improvement so an economical effect.